![]() However, approximately 80% of babies with Down’s syndrome are born to mothers under the age of 35. A 35-year-old woman has a one in 338 chance and a 45-year-old woman has a one in 32 chance. The chance of having a baby with Down’s syndrome increases when the mother is over 35 years of age. If you already have a child with Down’s syndrome, there’s a 1% increased risk of you having another baby with the condition. There is nothing you can do to prevent Down’s syndrome from occurring. What will increase the chance of my child having Down’s syndrome? Approximately 2% of people with Down’s syndrome have Mosaic Down’s syndrome Mosaic Down’s syndrome normally causes milder symptoms. Mosaic: Mosaic Down’s syndrome occurs when only some of the cells have an extra, third, chromosome 21.Approximately 4% of people with Down’s syndrome have translocation Down’s syndrome. This means people with translocation Down’s syndrome have the normal two copies of chromosome 21, but also have extra chromosome 21 material from the chromosome that has attached itself. ![]() Translocation: Translocation Down’s syndrome occurs when extra chromosome 21 material attaches itself to another chromosome.Approximately 94% of people with Down’s syndrome have regular trisomy 21 Down’s syndrome. There should be two copies of chromosome 21 in each cell, but people with regular trisomy 21 Down’s syndrome have three in each cell. Regular trisomy 21: Regular trisomy 21 Down’s syndrome occurs when all the cells in your body have an extra chromosome 21.Causes Causes of Down’s syndromeĭown’s syndrome is a genetic condition that occurs because of an extra chromosome. Many people with the condition can still learn all of the physical, mental, and social skills that most other people acquire they just do it at a different pace. If your child has Down’s syndrome, it will not stop them from developing at all. All people with Down’s syndrome will have some degree of learning disability, although some people are more severely affected than others. For example, it might take them longer to learn to speak, or to read. They may also be slower to develop socially and mentally. The physical development of children with Down’s syndrome tends to be slower than that of other children of a similar age. loose joints (babies in particular may seem ‘floppy’),.vertical skin folds (epicanthic folds) between the upper eyelids and inner corner of the eye,.broad hands with a single crease across the palm,.white spots on the iris (the coloured part of the eye), known as Brushfield spots,.However, there are treatments that can help someone with the syndrome to lead an active and independent life. There is currently no cure for the condition. The severity of Down’s syndrome symptoms can vary from person to person. However, due to a better understanding of the condition and advancements in treatment and care, the average life expectancy of someone with Down’s syndrome is now 60-65 years of age. In the 1950s, many people with Down’s syndrome did not live past the age of 15. Down’s syndrome occurs when a baby inherits an extra chromosome. It is a lifelong condition, present from birth. It is estimated that there are approximately 60,000 people with Down’s syndrome currently living in the UK.ĭown’s syndrome affects your physical appearance, as well as your ability to learn and develop mentally. The condition tends to affect male and females equally. Licence: (CC By-NC-ND 4.It affects approximately one in every 1,000 babies, which means that about 600 babies with Down’s syndrome are born each year in the UK. An introductory review – Scientific Figure on ResearchGate. I adore going to kinder and making new friends wherever we go.įind out more about isochromosomes on Wikipedia. I talk a lot, I love imaginative play, and the beach is always my happy place. Today I am a happy, energetic and busy little kid. So, I have a mosaic, isochromosome arrangement of my 21st chromosome which is incredibly rare! Two of these fused together and the other one lost its p arm. They have two parts: a long arm known as the ‘q arm’ and a short arm known as the ‘p arm’.Īt some point in the early days of my development before I was born, I ended up with three copies of the long q arm of my 21st chromosome. I have what is known as an isochromosome.Ĭhromosomes are thread-like structures in the cells that hold the genes. Roughly 2% of people diagnosed with Down syndrome have this variant.Īfter I was born, my blood test showed that the arrangement of my 21st chromosome is super rare. The rest of my cells have the usual two copies. ![]() But only some of my cells have a third copy of the chromosome 21.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |